Considering the bullet / powder makers have spent millions of dollars testing and measuring safe loads, I never exceed the listed loads in the books , and if pressure signs appear before the max load is reached I back off until it is gone.
The #1 rule I was taught many years ago is never try to be smarter than the books.
So far I haven't had a single issue with a load being adequate to kill or safe for the gun and the shooter, me.
I don't want to be that guy with a rubber mallet, or 2x4 beating his bolt open or looking for a drive to the hospital.
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