I started using a 6.5x55 some 35 years ago,i bought 2 around that time so my wife and I used the same cartridge to hunt with.She took 5 moose with hers and I shot my share with mine.Sold them both about ten years ago and bought a new tikka in 6.5 x55 and it is smack on,there's not many bullets it doesn't like.
For a cartridge that came out in 1894 it sure has seems to be holding up with anything new,infact there's guys looking for tikka's in this cartridge all the time.