338x250gnx2900fps in a 12-pound rig. That's a lot of juice at 50 yards for any irritated creature. Lots of punch out to 500 yards, controllable, nice and flat shooting too. No need for 375HH.
Caveat - I don't go out of my way to get close up and personal with grizzlies/brown bears, African cats, vindictive cape buffalo, etc etc. If I wanted to get something silly I would probably bypass the 375 and go directly to a 408 Cheytac, 458 Lott, or 50BMG. Kinda hard to swing a 50 around quickly in heavy bush though.
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