BC's don't mean much until you get over 500 yards. Sure a higher BC's will be flatter shooting slightly but if you know your rifle you should know where it shoots at those ranges, but like the difference in ballistics of a 7mm Rem Mag and a 280 Rem shooting the same bullet the ballistics will be different. So all the focus on high BC is a lot of marketing.
I think the quality of bullets has let smaller caliber and lighter bullets be used for larger game applications as they penetrate well however there will always be a want and desire to smack game with huge energy.
30 cal is king and always will be.
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