I'd use the heaviest bullet the rifle would stabilize. You can load some 250 gr. in there, that might be the ticket. 250gr. for the .300 anyway, or maybe a 220 for the 30-06. Degrease the bolt and give is a little shot of graphite.
JMO, but I would pass on "light" 180 gr. bullets and Nosler Partitions. With due respect to the partitioned bullet; they have killed a pile of game, but the whole front end is constructed light so that they will expand on smaller game at long range. And designed so that the whole front end can separate from the back, and leaving it do penetrate. The game you're after is big and tough, and likely fairly close, so it's a certainty that the whole front of the Partition will be shed.
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