NICE trip. Drive the coast highway as others have said. That was my honeymoon. Do NOT go inland. That is the fast but boring way. Look for the town that stakes it's claim on kites. I don't remember the name. Google it. And buy a kite.
stop in Sea Gulch and take a picture with both your faces in the wooden cut-outs. Just do it. I can't explain it.
Stay in Tillamook Oregon.
Vegas, who cares where you stay? On the strip for sure but go downtown to old Vegas for a couple hours, the old original casinos, then see a Cirque Du Soliel show (your wife will cry at "Love", and you will think the money spent on expensive tickets was well worth it), a 60's R&B lounge act, and a female impersonator show and you will have done it all. Eat breakfast at the Peppermill on the Strip. The omlette was HUGE. We asked how many eggs were in it. TEN! F'ING TEN EGG OMLETTES!!!!!!
ok, I'm done.