I've shot a 280 AI for a number of years. If there's one issue with it is that its almost too good as a do it all round, if that's even possible. I bought smaller and larger calibers and sold them off because my ackley could do it all. I then decided I WANTED something bigger, not to replace by any means but just because. I had an itch for a 338 so going that route.
You could do a 338 WM, base barrel length and twist on desired performance and ease of carrying/weight then play around with the newer powders and bullets.
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