I personally own rifles chambered in 18 different calibers and have done alot of big game hunting during my years either guiding or my own personal hunts.
It's funny but when I open up my gun safes.....I generally reach for one of my three different .270s
I'm currently busy loading and shooting a nice 24" barreled 7mm-08 to see how it will perform....but I can assure you that a quality 150 grn hunting bullet out of a .270 will kill moose as dead as anything else inside of 325 yds. if the shooter does his part and places the shot.
My all out honest recommendation is to shoot the rifle you shoot best ! Either of these calibers will take moose with a good bullet and shot placement.
Best of luck on your hunt and don't be afraid to spend a few days shooting at the range before hand.
