My rule of thumb is get poweder you can always get and is available most places most times of the year. Or get it in bulk.
That pretty much rules out the RL powders since they are a PITA to get in bulk, and their supply cycles too much for my liking.
And this is from a guy who loved RL22 in his 300Win Mag, and 284Win.
I've since gone to Hodgdon or IMR, both can be had in bulk here:
www.higginsonpowders.com/.../index.htm
As suggested try either 4350(load data is'nt interchaingable)
Might also consider both 4831's(same caveat as above).
Try here for load data:
data.hodgdon.com/cartridge_load.asp