What Tacklerunner said EXCEPT I am not a fan of Cortland lines (I have the sink-tip version of that line and the floating portion sucks goat balls!), so I recommend a RIO Aqualux or their camo version.
The full sink is better then the sink tip for most lake fishing. The Intermediate sink rate is excellent for working flies in shallow water, weed beds, or the top few feet of the water column. If you want to fish deeper in still water (from shore) with the full sink you just wait longer before beginning your retrieve. If you have the sink tip you can get the fly down fairly deep, but as soon as you start your retrieve you will pull your fly out of the productive zone (usually).
The sink-tip version is a lot nicer to use in moving water.
I have only started "seriously" fishing lakes in the last few years and am at 7 lines for fishing lakes. If need be, a good floating line and a intermediate full sink (preferably clear/camo) line will allow you to fish, in some manner, most of a lake, and I would highly recommend getting those 2 lines first. Then, I would get a fast full sink (Type 5 or 6), then a Type 3.
And remember: with a full sink line (especially the clear/camo) using a leader is unnecessary, and counterproductive. On my clear lines/tips I use 2 feet of tippet. One the dark lines I use 3-4 feet, often with a heavy but section (15-20lb) of 2 feet, then 2 feet of appropriately sized tippet; I am usually using larger flies with these lines (buggers, muddlers, boobys, dragonflies).
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