I have an Eskimo 9416i and an Otter Vortex Resort I just picked up this Fall. If you know you're going out with two people, I'd likely give the nod to the double hub style. They allow you to have a separate sleeping area and fishing area...at least that's how we use ours. If you plan to be out alone more often than not, I'd go with a big hex hub like the Otter Resort or Eskimo 650XD (which is why I bought mine). There is plenty of room for one person (single hubs like the Eskimo 949 or Otter Lodge are too small for overnighting IMO). Both types are big and heavy when you're out alone, but the hex hubs are easier to manhandle alone.
Wind is wind. They should all be fine if you anchor them down completely (Otter's system is better than Eskimo's). With a double hub system you can "point" it into the wind. With a hex hub you obviously can't, but it does provide a better profile to begin with.
I think the hex hubs are more versatile. I agree with Clayton Schick when he said in one of his
recent videos that if he could keep only one hub shelter it would be his Vortex Resort. He also has the Vortex Monster Lodge.