Unless you are shooting field mice the difference is irrelevant, but dead on at 200 would make you about a half inch high at 50. I sight all of my guns to hit 3.5" high at 100 yards, so I don't have to remember different drops for close shooting with different calibers. The 3.5" high at 100 puts most modern high speed rounds back dead on somewhere between 260 and 300 yards. Means that for deer sized game you can pretty much ignore the actual range and hold dead on to about 340 yards, which is lots far enough for 98% of the game that gets shot every year.
Drop chart for a .308 bullet doing 3000 FPS and a BC in the 420 range.
Muzzle -1.5
25 0.1
50 1.5
100 3.5
125 4.1
150 4.4
175 4.4
200 4.0
225 3.4
250 2.4
275 1.0
300 -.08
325 -2.9
350 -5.4
375 -8.4
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